Maintenance of membrane integrity and proton motive force (PMF) is critical for bacterial survival. The phage shock protein (Psp) system, conserved across bacterial species, stabilizes the membrane, maintains PMF, and …
The rapid global expansion of antimicrobial resistance (AMR) threatens to undermine decades of progress in infectious disease management and highlights the limitations of conventional antibiotic-centered therapeutic strategies. Although emerging technologies-including …
CONCLUSION: For recalcitrant prosthetic joint infections, treatment with bacteriophage as an adjuvant to care can drastically modify the clinical course.
Breast implant infection and capsular contracture remain significant complications of implant-based breast surgery, largely driven by bacterial biofilm formation. Despite adherence to perioperative antibiotic prophylaxis and pocket irrigation protocols, established …
Genetic code expansion introduces new-to-nature chemical moieties into ribosomally synthesized proteins. In practice, the scope of functional groups that can be accessed using this method is often limited by noncanonical …
Antimicrobial resistance (AMR) is driven not only by antimicrobial use but also by the horizontal transfer of resistance genes between bacteria. Conjugative plasmids are key drivers of this process, facilitating …
As the crisis of antibiotic resistance escalates, phage therapy has regained attention as an alternative strategy. Artificial intelligence (AI) technologies offer new avenues to overcome the bottlenecks inherent in traditional …
Southeast Asia faces a substantial burden of antimicrobial resistance (AMR), creating increasing interest in bacteriophage-based antimicrobial strategies. However, the regional development, contributors, collaboration patterns, and evolving research priorities of this …
Antimicrobial resistance in multidrug-resistant Escherichia coli has severely compromised the efficacy of conventional antibiotics, particularly in hospital-acquired infections. Bacteriophage therapy offers a targeted approach, yet the rapid emergence of phage-resistant …
The emergence of antimicrobial resistance in extraintestinal pathogenic Escherichia coli (ExPEC) necessitates alternative therapies for swine. Two lytic phages, vB_EcoM_S37 and vB_EcoP_S37A, were isolated from swine wastewater and characterized for …
One Ecosystem | Three Platforms
